Brazil

Crop Coverage

Our services span across all major crops in the country, including but not limited to Soybean, Maize, Cotton, Sugar-Cane, Rice, Wheat, Citrus, Coffee, Grapes, Tropica Frutis, Potato, Tomato and other Vegetables.

Efficacy Studies / Product Performance

SynTech Research Brazil evaluates product performance across the entire development pipeline: from early-stage screening and proof of concept to advanced trials supporting regulatory submissions.

The work covers a broad range of agricultural inputs, including seeds and traits, chemical and biological fungicides, insecticides and nematicides, herbicides, biocontrol inputs, biostimulants, growth regulators, inoculants, resistance inducers, fertilizers, peptides, metabolites, soil amendments, among others. This scope continues to evolve as new technologies and innovative solutions emerge in the market.

SynTech supports clients with study design and protocol development tailored to each stage of product development, ensuring scientifically robust and regulatory-aligned approaches. The team of specialists across disciplines, including entomology, nematology, plant pathology, and plant physiology, provides technical guidance to optimize trial design, data generation, and product positioning.

SynTech Research offers a full range of experimental platforms:

• Laboratory and in vitro studies, including microbiology capabilities for inoculum production and rapid screening assays to support dose definition, mode of action understanding, and early product selection.
• Greenhouse trials, enabling controlled-condition studies and accelerated testing when field conditions are limiting.
• Field trials, ranging from small research plots to large-scale trials designed to support regulatory requirements and product positioning.

The organization also conducts physical-chemical and biological compatibility studies, both under laboratory conditions and in tank-mix scenarios, supporting formulation development and practical field application strategies.

All studies are conducted with a focus on data quality, regulatory compliance, and operational efficiency. SynTech is certified under Brazilian Ministry of Agriculture (MAPA) standards, including IN 36/42 (control and biocontrol products) and IN 53 (fertilizers and biofertilizers), and delivers official reports to support product registration.

From early insights to regulatory-ready data, SynTech provides integrated study management to accelerate development timelines and support confident decision-making.

Residue Studies (GLP)

SynTech offers fully integrated residue study programs, covering all phases from protocol development and field trials to sample analysis and final report preparation. Studies are conducted under Good Laboratory Practices (GLP), with certification granted by INMETRO since 2010, and are designed to meet both Brazilian and international regulatory requirements, including ANVISA, EPA, SANTE, and OECD guidelines.

Supported by a highly experienced team and strong nationwide operational coverage, SynTech ensures efficient study execution across diverse agricultural regions, maintaining consistency and reliability throughout all stages.

The analytical laboratory, located in Piracicaba, is widely recognized by clients as one of the leading CRO facilities in Latin America, equipped with state-of-the-art technology and advanced analytical capabilities to ensure high precision and data integrity.

SynTech Research conducts a comprehensive range of residue studies, including:

• Crop Residue Studies
  Evaluation of residues in major agricultural commodities such as grains, fruits, and vegetables, supporting regulatory submissions and MRL establishment.
• Studies on Regulated Materials (GMOs) / Stewardship
  Residue evaluation in genetically modified crops not yet commercially released, supporting product development, stewardship programs, and regulatory approval processes.
• Bee Residue Studies
  Assessment of residues in bee-related matrices, including pollen, nectar, and bees, supporting environmental and pollinator safety evaluations.
• Soil Residue Studies
  Investigation of product persistence and behavior in soil under field conditions.
• Frozen Storage Stability & Analytical Support
  Determination of residue stability in stored samples to ensure data integrity over time, combined with analytical method development, optimization, and validation in compliance with regulatory standards.
• Processing Studies
  Evaluation of residue behavior during industrial and household processing, including transformation into derived products such as juices, oils, sugar, soluble coffee, and other processed fractions.

SynTech is committed to delivering high-quality, reliable, and timely results, supporting regulatory compliance and contributing to the safe and responsible use of agricultural products.

Ecotoxicology Studies (GLP)

SynTech conducts GLP-compliant ecotoxicology studies to support Environmental Risk Assessment (ERA) of agrochemicals, with a strong focus on pollinator safety. Our studies are aligned with Brazilian regulatory requirements, including IBAMA Instruction Normative No. 2 (February 9, 2017), as well as relevant international guidelines.

Supported by experienced specialists and strong operational coverage across key agricultural regions, SynTech ensures studies are conducted under representative field conditions, with careful planning and execution to reflect realistic exposure scenarios.

A key differentiator of our program is the rigorous selection, handling, and management of bee colonies, combined with deep technical expertise in pollinator studies. We have also developed specialized methodologies for extraction and analysis of bee-related matrices, such as pollen and nectar collected directly from treated crops, ensuring high-quality and reliable data.

Services include:

• Tier 1 – Laboratory Studies
  Toxicity to bees from foliar residues RT25 (OPPTS 850.3030)
• Tier 2 – Residue Studies in Bee Matrices
  Determination of residues in pollen and nectar under field conditions
• Tier 3 – Semi-field Studies (Tunnel Tests)
  Higher-tier studies to refine risk assessment when effects cannot be ruled out in earlier phases, following EPPO, EFSA, and US-EPA guidance
• Advanced Studies
  Larval development and behavioral assessments under semi-field or open-field conditions (OECD 75, EPPO 170)

In addition to study execution, SynTech supports clients with protocol design aligned to regulatory expectations and delivers high-quality, audit-ready reports. Our team also provides post-study technical support, assisting clients in responding to regulatory authorities and ensuring confidence in the generated data.

With a stable and experienced team, SynTech acts as a reliable long-term partner for ecotoxicology programs, combining scientific rigor, operational consistency, and regulatory expertise.

Studies with Seeds and Traits (GMOs)

SynTech conducts studies with genetically modified crops under full compliance with Brazilian biosafety regulations. The company is accredited with the Certificate of Biosafety Quality (CQB) issued by CTNBio since 2019, reinforcing its commitment to high standards in handling regulated materials.

Supported by a highly experienced team and strong operational coverage across multiple agricultural regions, SynTech ensures the safe, compliant, and efficient execution of studies under diverse environmental and agronomic conditions. Our team combines technical expertise with a solid track record in biosafety, providing clients with confidence throughout all stages of development and regulatory assessment.

Capabilities include:

• Compositional, Expression, and Agronomic Studies
  Evaluation of protein expression levels, compositional equivalence, and agronomic performance to support regulatory submissions.
• Non-target Organism (NTO) Studies
  Assessment of potential effects of traits on non-target species, supporting environmental risk evaluations.
• Degradability and Microbiota Studies
  Evaluation of biodegradability and potential impacts on soil microbiota.
• Efficacy Trials and VCU (Value for Cultivation and Use)
  Field evaluation of seeds and traits performance, including insect resistance and herbicide tolerance, as well as VCU studies required for variety registration in Brazil.
• Trait Screening and Protein Efficacy
  Early-stage and advanced testing to support selection and characterization of new technologies.
• Seed Production for Research
  Support for breeding programs and seed supply, including foundation seed and operational seed increase for varieties, hybrids, and cultivars, enabling field trials and regulatory studies across different development stages and regions.

SynTech supports both regulated and deregulated materials, providing integrated solutions from early-stage evaluation to studies designed for registration and commercialization. In addition to study execution, SynTech offers protocol development aligned with regulatory expectations and delivers high-quality, audit-ready reports.

With recognized expertise in biosafety and a consistent, experienced team, SynTech acts as a reliable partner for the development, validation, and advancement of seed and trait technologies.

Regulatory Services

SynTech provides comprehensive regulatory support for agrochemical, biological, and fertilizer products, combining technical expertise with a strategic, client-focused approach. Our multidisciplinary team works as an extension of our clients’ organizations actively contributing to the successful positioning and approval of each product.

The teams support clients throughout the entire regulatory lifecycle, from early development stages to post-registration, ensuring alignment with Brazilian requirements while anticipating challenges and opportunities.

Regulatory services include:

• Regulatory Strategy and Advisory
  Interpretation of local legislation and guidance on regulatory pathways, supporting informed decision-making and efficient development plans.
• Registration Project Management
  End-to-end coordination of registration projects, including dossier review and gap analysis, monitoring of local studies, technical support for dossier preparation, and submission management.
• Regulatory Dossier Support and Defense
  Preparation, review, and technical defense of dossiers, ensuring consistency, quality, and readiness for regulatory scrutiny.
• Process Monitoring and Agency Interaction
  Tracking of approvals, timelines, and regulatory milestones, with active follow-up and communication with authorities when required.
• Full Lifecycle Support
  Assistance at every stage, from Experimental Use Permit (EUP) to federal registration, including post-submission demands, registration maintenance, and state-level registrations.

SynTech Research goes beyond standard consultancy: The team combines regulatory, agronomic, and scientific expertise to deliver tailored solutions, helping clients navigate complexity, mitigate risks, and accelerate time-to-market. This integrated and proactive approach establishes SynTech as a trusted partner for successful product registration in Brazil.